James C Sacchettini Selected Research

beta-ketoacyl-acyl carrier protein synthase I

2/2007

X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB).

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James C Sacchettini Research Topics

Disease

62	Tuberculosis (Tuberculoses) 10/2022 - 10/2002
18	Infections 01/2022 - 04/2006
4	Neoplasms (Cancer) 03/2018 - 01/2015
4	Persistent Infection 01/2018 - 01/2003
3	Starvation 01/2022 - 01/2008
3	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 04/2016 - 01/2012
3	Malaria 02/2013 - 04/2002
2	Communicable Diseases (Infectious Diseases) 10/2021 - 01/2009
2	Neoplasm Metastasis (Metastasis) 03/2018 - 06/2016
2	Bacterial Infections (Bacterial Infection) 01/2013 - 07/2010
1	Cardiotoxicity 10/2022
1	Menkes Kinky Hair Syndrome (Menkes Disease) 01/2020
1	Hypoxia (Hypoxemia) 12/2018
1	Rabies (Hydrophobia) 08/2015
1	Latent Tuberculosis 05/2011
1	Poisoning 05/2010

Drug/Important Bio-Agent (IBA)

22	Pharmaceutical PreparationsIBA 01/2021 - 01/2004
19	EnzymesIBA 10/2022 - 01/2003
11	Proteins (Proteins, Gene)FDA Link 10/2021 - 02/2008
9	Isoniazid (Ftivazide)FDA LinkGeneric 01/2022 - 06/2003
6	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 03/2005
5	Oxidoreductases (Dehydrogenase)IBA 04/2015 - 06/2003
5	Fatty Acids (Saturated Fatty Acids)IBA 07/2013 - 04/2002
4	Antitubercular AgentsIBA 06/2016 - 01/2009
3	Rifampin (Rifampicin)FDA LinkGeneric 01/2018 - 06/2016
3	glyoxylic acid (glyoxylate)IBA 01/2017 - 01/2003
3	Mycolic Acids (Mycolic Acid)IBA 07/2013 - 08/2004
2	LipidsIBA 10/2022 - 10/2021
2	HydrolasesIBA 10/2021 - 01/2018
2	Pyrazinamide FDA LinkGeneric 01/2020 - 01/2017
2	CopperIBA 01/2020 - 02/2014
2	Phosphotransferases (Kinase)IBA 03/2018 - 06/2016
2	Biotin (Vitamin H)FDA Link 11/2017 - 08/2010
2	Isocitrate LyaseIBA 01/2017 - 01/2003
2	Acyl Carrier ProteinIBA 04/2015 - 04/2006
2	Triclosan (pHisoHex)FDA Link 02/2013 - 07/2007
2	Malate SynthaseIBA 12/2012 - 01/2003
2	beta-Lactamases (beta-Lactamase)IBA 07/2010 - 08/2006
2	TrehaloseIBA 05/2010 - 08/2004
2	Amyloid (Amyloid Fibrils)IBA 11/2003 - 04/2002
1	Virulence Factors (Pathogenicity Factors)IBA 10/2022
1	phosphopantetheinyl transferaseIBA 10/2022
1	benzamideIBA 10/2022
1	Ion Channels (Ion Channel)IBA 10/2022
1	ProdrugsIBA 10/2021
1	LyasesIBA 01/2021
1	isocitric acid (isocitrate)IBA 01/2021
1	bedaquiline (R207910)IBA 11/2020
1	LactamsIBA 01/2020
1	elesclomolIBA 01/2020
1	NitrogenIBA 01/2020
1	Peptidoglycan (Murein)IBA 01/2020
1	Peptidyl Transferases (Peptidyltransferase)IBA 01/2020
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2020
1	SilverIBA 01/2019
1	SiderophoresIBA 01/2019
1	IronIBA 01/2019
1	purineIBA 01/2019
1	CationsIBA 01/2019
1	Chelating AgentsIBA 01/2019
1	Lysine AcetyltransferasesIBA 12/2018
1	Ethambutol (Myambutol)FDA LinkGeneric 01/2018
1	Serine (L-Serine)FDA Link 01/2018
1	TAM16 compoundIBA 07/2017
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 01/2017
1	Palmitic Acid (Hexadecanoic Acid)IBA 01/2017
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2017
1	Protein Synthesis InhibitorsIBA 10/2016
1	Streptomycin (Streptomycin Sulfate)FDA Link 10/2016
1	Small Interfering RNA (siRNA)IBA 08/2015
1	Dyneins (Dynein)IBA 08/2015
1	Type VII Secretion SystemsIBA 04/2015
1	Malonyl Coenzyme A (Malonyl CoA)IBA 10/2014
1	haloxyfopIBA 10/2014
1	HerbicidesIBA 10/2014
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 10/2014
1	beta-LactamsIBA 01/2014
1	Tryptophan (L-Tryptophan)FDA Link 12/2013
1	Heme (Haem)IBA 09/2013
1	ThioredoxinsIBA 09/2013
1	Cytochromes c (Cytochrome c)IBA 09/2013
1	CytochromesIBA 09/2013
1	Biological ProductsIBA 06/2013
1	GlycolipidsIBA 06/2013
1	CorrinoidsIBA 02/2013
1	VitaminsIBA 02/2013
1	Peptides (Polypeptides)IBA 01/2013
1	Biomarkers (Surrogate Marker)IBA 01/2013
1	AntibodiesIBA 01/2013
1	Complement System Proteins (Complement)IBA 11/2012
1	shikimateIBA 06/2011
1	Cycloserine (Seromycin)FDA Link 01/2011
1	Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA 09/2010
1	4,4-difluororetinoic acidIBA 09/2010
1	Fluorescent Dyes (Fluorescent Probes)IBA 07/2010
1	VaccinesIBA 07/2010
1	GlucansIBA 05/2010

Therapy/Procedure

11	Therapeutics 01/2020 - 07/2010
5	Drug Therapy (Chemotherapy) 01/2022 - 01/2008
1	Radiotherapy 01/2015